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Starting with a small dose allows the body to adjust to the medication

This represents the most common starting point in practical protocols and aligns with the midpoint of clinical dosing ranges adjusted for average body composition

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Tendon fibroblast migration : Moving healing cells directly to an injured tendon

Peak at 3-6 months

Some sensitive patients may benefit from microdosing (below 0.25 mg) or customized compounded formulations to improve tolerance